Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87a863132c68cf0f62015bbd5d05ab38 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39591 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
filingDate |
2008-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45d4a63e82887b11ebf40e4337ba26e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_394a0a5e8761d617aabd60cae61dc8e9 |
publicationDate |
2017-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2637918-T3 |
titleOfInvention |
Methods and structural conformations of antibody preparations with increased protease resistance |
abstract |
A protein preparation containing glycosylated IgG Fc, in which one or more Fc residues in the CH2 region of the glycosylated Fc-containing protein are mutated to maintain or increase hydrophobic interactions and decrease hydrophilic interactions in CH2 regions or CH3 in which the mutations are Lys 246 Ala, Thr 260 Ala, and / or Arg 301 Ala. |
priorityDate |
2007-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |