abstract |
A compound of Formula A ** Formula ** wherein R1 represents triazolyl or oxadizolyl, said triazolyl or oxadizolyl may optionally be substituted with 1 group R5, X represents N or CH when R1 is triazolyl or when R1 is oxadiazole X represents CH, R5 represents C1-C6 alkyl, C3-C6 cycloalkyl or a 5-6 membered heterocyclic ring with 1 or 2 heteroatom (s) selected from N, O or S, said cycloalkyl or heterocyclic ring is optionally substituted with 1 or 2 C1-C3 alkyls or 1 or 2 C1-C3 alkoxy, R2, R3 and R4 each independently represent hydrogen, halogen, C1-C6 alkyl, C1-C6 alkoxy, O (CH2) nCF3, (CH2) nR6, (C> = O) R6 or (CH2) n (C> = O) R6, n> = 0, 1, 2 or 3, or R2 and R3 or R3 and R4 can form together with the atom to which they are attached a bicyclic heterocyclic ring of 9-10 members with 1 or 2 heteroatom (s) selected from N, O or S, said bicyclic heterocyclic ring may be optionally substituted with 1 or 2 C1-C6 alkyl or 1 or 2 C1-C6 alkoxy, R6 represents a 5-6 membered heterocyclic ring with 1, 2 or 3 heteroatom (s) selected from N, O or S, said heterocyclic ring may be optionally substituted with 1 or 2 C1- alkyl. C3 or 1 or 2 C1-C3 alkoxy, and the pharmaceutically acceptable salts thereof. |