| abstract |
A compound of formula (I) ** Formula ** in which A is CH2 or is absent; R1 and R2, together with the nitrogen atom to which they are attached, form 2-oxa-6-azaspiro [3.3] substituted heptyl or pyrrolidinyl, in which substituted pyrrolidinyl is pyrrolidinyl substituted with one or two substituents independently selected from halogen, hydroxyl and alkylcarbonyloxy; and R3 is halophenyl, alkylsulfonylphenyl, haloalkylphenyl, halopyridinyl, alkyloxyadiazolyl, alkyltriazolyl, alkyltetrazolyl, oxolanyl, cycloalkyltetrazolyl or haloalkyl-1H-pyrazolyl; or a pharmaceutically acceptable salt or ester thereof. |