abstract |
A microneedle drug delivery system for transdermal or topical administration of a cannabidiol prodrug to a mammal, comprising: a) a pharmaceutical composition comprising a cannabidiol prodrug having the formulas: ** (See formula) ** wherein X- is a counter ion derived from pharmaceutically acceptable acids, and b) a microneedle matrix, wherein the pharmaceutical composition is for administration to the mammalian skin together with the microneedle matrix, before administration of the microneedle matrix , after administration of the microneedle matrix or simultaneously with the administration of the microneedle matrix. |