http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2633732-T3

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filingDate 2012-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d191e1b6edaf82ab42299754cc9fed38
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publicationDate 2017-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2633732-T3
titleOfInvention Procedure and kit to determine in vitro the immune status of an individual
abstract Procedure to determine in vitro the overall immune status of a septic individual for the implementation of the best possible therapy based on the established immune response according to which: a. a blood sample of the individual is available, b. There are at least two specific reagents of at least two expression products of at least two target genes respectively selected from the following target genes: HLA-DRA, S100A9, S100A8, IRAK-M, LY64, CIITA, TNF-alpha, IL -10, GBP1, MMP7, CXCL1, CXCL10, COX2, FCN1, TNFAIP6, CXCL7, CXCL5, PID1 and RHOU, c. the expression of said at least two target genes is determined, and d. the expression of said at least two target genes respectively is compared with a reference expression, a modification in the expression of said at least two target genes with respect to their reference expression being an indicator of a modification of the individual's immune status, and being a correlation between the expression of said at least two target genes with their reference expression an indicator of a normality of the individual's immune status.
priorityDate 2011-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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