Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25c4fc4e202922a16436d7d118f2043e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2887 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 |
filingDate |
2010-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c0f16accb48d5c8ed3c62caa4321b95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f683fa1861240bb36eae2f829516b77 |
publicationDate |
2017-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2630158-T3 |
titleOfInvention |
Combined therapy of a CD20 antibody afucosylated with bendamustine |
abstract |
Use of an afucosylated anti-CD20 antibody with a quantity of fucosa of 60% or less of the total quantity of oligosaccharides (sugars) in Asn297, for the manufacture of a medicine for the treatment of cancer in combination with bendamustine, characterized in that said cancer is a cancer that expresses CD20 and because said antibody comprises an amino acid sequence of the variable region of the heavy chain (VH) of SEQ ID NO: 7 and an amino acid sequence of the variable region of the light chain (VL ) of SEQ ID NO: 20. |
priorityDate |
2009-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |