http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2630062-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a47fb531c4bad7aa7bffd78768256eb |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 |
| filingDate | 2013-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c65933ea9ce400994e06c3ef3fd378f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61bef33016289a04bd6b163f43dddb00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8485e3673f2aa1ded4d21befabcfe262 |
| publicationDate | 2017-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2630062-T3 |
| titleOfInvention | Histone Deacetylase Inhibitors (HDAC) |
| abstract | A compound of formula X: ** Formula ** or a pharmaceutically acceptable salt thereof, (I) wherein: R1 is hydrogen, (C1-C6) alkyl, or (C3-C6) cycloalkyl; R2 is (C6-C18) aryl, (C6-C18) aryl (C1-C6) alkyl, (C3-C18) heteroaryl (C1-C6) alkyl, (C6-C18) haloaryl - (C1-C6) alkyl, or (C1-C6 alkoxy) aryl (C6-C18) (C1-C6) alkyl; R3 is N-hydroxyamino-oxo-alkenyl (C2-C6); R4 is hydrogen, halogen, N-hydroxyamino-oxo-alkenyl (C2-C6), or N-hydroxyaminocarbonylaryl (C6-C18) alkylene (C1-C6); R5 is hydrogen, halogen, N-hydroxyamino-oxo-alkenyl (C2-C6), N-hydroxyaminocarbonylaryl (C6-C18) alkylene (C1-C6), or aminoaryl (C6-C18) -oxo-alkenyl (C2-C6) ; and R6 is hydrogen, N-hydroxyamino-oxo-alkenyl (C2-C6), N-hydroxyaminoaryl (C6-C18) alkylene (C1-C6), 4- (N hydroxyaminocarbonyl) phenyl, or N-hydroxyaminocarbonylaryl (C6-C18) (C1-C6) alkylene; or (II) where: R1, R2, R5 and R6 are each as defined in (I) above; R3 is hydrogen or N-hydroxyamino-oxo-alkenyl (C2-C6); and R4 is N-hydroxyamino-oxo-alkenyl (C2-C6), or N-hydroxyaminocarbonylaryl (C6-C18) alkylene (C1-C6); or (III) where: R1, R2, R4 and R6 are each as defined in (I) above; R3 is as defined in (II) above; and R5 is N-hydroxyamino-oxo-alkenyl (C2-C6), N-hydroxyaminocarbonylaryl (C6-C18) alkylene (C1-C6), or amino-aryl (C6-C18) -oxo-alkenyl (C2-C6); or (IV) where: R1, R2, R4, R5 are each as defined in (I) above; R3 is as defined in (II) above; and R6 is N-hydroxyamino-oxoalkenyl (C2-C6), N-hydroxyaminoaryl (C6-C18) alkylene (C1-C6), 4- (N-hydroxyaminocarbonyl) phenyl, or N-hydroxyaminocarbonylaryl (C6-C18) alkylene (C1 -C6). |
| priorityDate | 2012-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 210.