abstract |
A ligand comprising an individual variable domain of antibodies, wherein said individual variable domain of antibodies comprises the amino acid sequence of dAb7h14 having the amino acid sequence depicted in Figure 24, Sheet 1, or an amino acid sequence that is identical to the same at least in 95%, where the beta T half-life of the individual variable domain in cynomolgus is at least 50% of the beta T half-life of cynomolgus serum albumin in cynomolgus. |