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filingDate 2009-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9b2a1db0a494818d8cbee4dac5c6c57
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publicationDate 2017-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2628100-T3
titleOfInvention Compositions comprising decellularized extracellular matrix obtained from cardiac tissue
abstract A liquid composition comprising decellularized extracellular matrix derived from cardiac tissue, wherein the composition is suitable for administration through a needle catheter without obstructing the catheter, wherein the decellularized extracellular matrix can be obtained by a method comprising: (a ) processing a sample of cardiac tissue that has an extracellular matrix component and a non-extracellular matrix component to separate the non-extracellular matrix component to obtain decellularized extracellular matrix; (b) lyophilize and pulverize the decellularized extracellular matrix in a powder; (c) produce a composition comprising the extracellular matrix powder decellularized in a liquid; (d) digest the decellularized extracellular matrix in the composition of step (c) with a matrix degrading enzyme at pH 1-6; and (e) neutralizing the pH of the digested decellularized extracellular matrix of step (d) to produce the liquid composition; where the liquid composition becomes a gel at body temperature.
priorityDate 2008-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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