abstract |
Fluorescent nanoparticles containing an inorganic nucleus, a passivation layer containing an imidazole component, and specific ligands for a target molecule, with a hydrodynamic diameter of the inorganic nucleus with the passivation layer of not more than 15 nm, preferably not more than 10nm, particularly preferably not more than 5nm, for use as a marking in tissue diagnosis to discriminate different types of tissue in surgical, endoscopic or minimally invasive procedures, the nanoparticles presenting an emission of less than 700nm. |