| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db8acd71f5994544bda6df3f27a3f51e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-24121
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-24162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-24132 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-162
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-768
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7076
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-768
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
| filingDate |
2010-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4db2ba341fe002665dc832dcbe41c36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e8493ac9efe53f72b2a0e71bda96527 |
| publicationDate |
2017-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2626657-T3 |
| titleOfInvention |
Oncolytic viruses and methods to treat neoplastic disorders |
| abstract |
A poxvirus comprising a functionally inactivated small ribonucleotide reductase (R2) gene comprising a negative dominant mutation, a point mutation or a suppression mutation, in which the protein encoded by the functionally inactive R2 gene is capable of interacting with subunits of ribonucleotide reductase (RR) cell, and in which the protein lacks at least 2 amino acids from the large binding domain to ribonucleotide reductase (R1), or in which the encoded protein comprises a mutation of Y300. |
| priorityDate |
2009-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |