| abstract |
An in vitro method to facilitate the diagnosis of lymphoplasmocytic lymphoma in a subject, the method comprising: determining whether there is a mutation at position 38182641 on chromosome 3p22.2 based on the NCBI Compilation 37 reference genome, in a biological sample of a subject who has one or more of the following clinical characteristics: anemia, hyperviscosity, neuropathy, coagulopathies, splenomegaly, hepatomegaly, adenopathy and a serum IgM paraprotein, in which the presence of the mutation is indicative that the subject has lymphoplasmocytic lymphoma. |