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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00
filingDate 2015-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abf95b53b031b54967c8c4ea7aac5cbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef58188343f003d27a25471d43d848ac
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publicationDate 2018-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2620905-B1
titleOfInvention Procedure to reduce ketones derived from vitamin D in continuous and procedure of manufacture of calcipotriol and corresponding use
abstract Procedure to reduce ketones derived from vitamin D in continuous and procedure of manufacture of calcipotriol and corresponding use. Procedure to reduce ketones derived from vitamin D of general structure (V) or (VI) with borohydrides, where R {sub, 1} and R {sub, 2} can be the same or different and represent hydrogen or hydroxyl protecting groups, for give compounds of general structure (III) and (IV) or (VII) and (VIII), useful as intermediates for the synthesis of calcipotriol, where the reduction reaction is carried out in a continuous flow reactor. This procedure can be used as part of a calcipotriol manufacturing process.
priorityDate 2015-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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