http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2619557-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9af4d89807e0db8298692dffeabf875 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D339-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-58 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D339-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428 |
| filingDate | 2010-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf7d046ec242dbddae266c5286606434 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec5f6bae763c7d340f4a7e845fadab44 |
| publicationDate | 2017-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2619557-T3 |
| titleOfInvention | PKM2 activators for use in cancer treatment |
| abstract | A compound selected from formula (I) or formula (II): ** Formula ** where: m is an integer from 0 to 5; each R1 is independently selected from a group C1-C6-alkyl, C1-C6-alkoxy, halo-C1-C6-alkyl, halo-C1-C6-alkoxy, halo, acetyl, -NO2, aryl, aralkyl, heteroaryl, -SO2-aryl, -C (O ) -NRb-aryl, -C (O) -aralkyl, -C (O) -C1-6alkoxy, - NRb-SO2-aryl, wherein each aryl, aralkyl, and heteroaryl is optionally substituted with 0-3 occurrences of Rc and wherein two R1 groups taken together with the carbon atoms to which they are attached form a heterocyclyl ring; n is an integer from 1 to 3; each R2 is independently selected from C1-C6 alkyl and halo; B is aryl, monocyclic heteroaryl, cycloalkyl, heterocyclyl, C1-6 aralkyl, or heteroaralkyl; L is a linker selected from -SO2-, -SO2NRa- and NRaSO2-; each Ra is independently selected from hydrogen and C1-C6 alkyl; where one of X and Y is O and the other is NRb or one of X and Y is S and the other is NRb; Z is O or S; each Rb is C1-C6 alkyl substituted with 0-1 occurrences of Rc; Rc is independently selected from C1-6alkyl, C1-6alkoxy, haloC1-6alkyl, halo, NRdRd, and heterocyclyl and wherein two Rc groups taken together with the carbon atoms to which they are attached form a heterocyclyl ring; and Rd is independently selected from H and C1-6 alkyl. |
| priorityDate | 2009-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 359.