http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2615581-B1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9beae656a28ded212cf39a4d26f76bfb
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-069
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-15
filingDate 2015-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e667c4291197de3606820d50e18e43f8
publicationDate 2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2615581-B1
titleOfInvention Procedure for the ex-vivo study of the initial response of different cell types in atherosclerosis
abstract Procedure for the ex-vivo study of the initial response of different cell types in atherosclerosis. # The novelty of this model lies in the incubation of the cells of interest with the complete secrecy of atheroma plaques to evaluate the cellular response. Such incubation allows to study more directly the cellular response against the factors secreted by atheroma plaques, instead of using isolated factors (VEGF, SDF-1). # This procedure would allow to evaluate strategies to modulate the cellular response in response to atherosclerotic damage, for example in the case of progenitor endothelial cells (ECPs), to enhance vascular remodeling in therapies based on the use of these cells, although it can also be applied to any cell type associated with atherosclerosis. It also allows evaluating the effect of drugs in this initial cellular response framework against atherosclerosis.
priorityDate 2015-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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