Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e70c0aeade92d7571d955d3b90ea06e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02E50-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1258 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y503-01005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y503-01006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y501-03001 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-06 |
filingDate |
2012-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0023d7504d553e2fe67df34c7319b9c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_debbb9151b7da9f9aa8e70a0f4c23469 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7010888277e6842101898fff176d15f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c932112d69ce7104c4ec37db77a8c7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0830be146eae41d4af75a225d01facce |
publicationDate |
2017-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2611977-T3 |
titleOfInvention |
Modification of the pnp gene for improved use of xylose in zymomonas |
abstract |
A recombinant bacterial host cell comprising: a) a xylose metabolic pathway comprising at least one polypeptide having xylose isomerase activity; b) at least one genetic modification that increases ribose-5-phosphate isomerase activity in the host cell compared to ribose-5-phosphate isomerase activity in the host cell that lacks said genetic modification, wherein said at least A genetic modification that increases ribose-5- phosphate isomerase activity is chosen from the group consisting of: i) overexpression of an endogenous gene encoding a polypeptide having ribose-5-phosphate isomerase activity; and / or ii) expression of at least one non-endogenous gene encoding a polypeptide having ribose-5- phosphate isomerase activity; and c) at least one genetic modification in the sequence of an endogenous gene encoding polynucleotide phosphorylase that shortens the coding region which results in the expression of a truncated C-terminal protein; wherein the bacterial host cell uses xylose to produce ethanol and the activity of xylose isomerase is not limiting in the bacterial host cell, where the activity of xylose isomerase is not limiting when an increase in the activity of xylose isomerase does not improve the use of Xylose and ethanol production in said cell. |
priorityDate |
2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |