| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e147579187072f52ecce6141da00c5fb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-193
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
| filingDate |
2011-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26b9acc26239edb2acf8c310b9b490ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ccb4f856747ba2db598f560aca093da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46c2dd4ea02b587635eceb706a265750
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1df361d3dad0ee7b05a480eb91d5b7dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2cac9aba9b512b5aa87c0e25eacbccf9 |
| publicationDate |
2017-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2611151-T3 |
| titleOfInvention |
Recombinant human G-CSF dimer and use thereof for the treatment of neurological diseases |
| abstract |
A dimer of the human granulocyte colony stimulating factor (G-CSF) of formula (I) (I) M1-L-M2 wherein M1 is a first G-CSF monomer; M2 is a second monomer of G-CSF; and L is a connector that connects said first monomer and said second monomer and is disposed between them; wherein L is a polypeptide of formula (II): (II) -Z-Y-Z in which Y is a carrier protein formed by two Fc fragments connected through a plurality of disulfide bonds arranged between them; and Z is a short peptide comprising from 0 to 30 amino acids; wherein said G-CSF dimer retains the biological activity of G-CSF and is produced by two G-CSF-Fc complexes, each of said G-CSF-Fc complexes comprising the amino acid sequence of SEQ ID NO: 6 . |
| priorityDate |
2010-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |