abstract |
A compound (2S, 3R) -N- (2 - ((3-pyridinyl) methyl) -1-azabicyclo [2.2.2] oct-3-yl) benzofuran-2-carboxamide or a pharmaceutically acceptable salt thereof, in an enantiomeric or diastereoisomeric excess of 90% or greater with respect to (2S, 3S) -N- (2 - ((3-pyridinyl) methyl) -1-azabicyclo [2.2.2] oct-3-yl) benzofuran-2 -carboxamide or a pharmaceutically acceptable salt thereof, (2R, 3S) -N- (2 - ((3-pyridinyl) methyl) -1-azabicyclo [2.2.2] oct-3-yl) benzofuran-2-carboxamide or one of its pharmaceutically acceptable salts, or (2R, 3R) -N- (2 - ((3-pyridinyl) methyl) -1-azabicyclo [2.2.2] oct-3- yl) benzofuran-2-carboxamide or one of its pharmaceutically acceptable salts, wherein the compound or its pharmaceutically acceptable salt, is an acid salt of (2S, 3R) -N- (2 - ((3- pyridinyl) methyl) -1-azabicyclo [2.2.2] oct -3-yl) benzofuran-2-carboxamide, whose acid is selected from the group consisting of sulfuric acid, phosphoric acid, maleic acid, toluenesulfonic acid, galactic acid (mucic acid), Dmandélic acid or, D-tartaric acid, methanesulfonic acid, R-10-camphorsulfonic acid and S-10-camphorsulfonic acid, ketoglutaric acid, and hippuric acid. |