| abstract |
An isolated neutralizing monoclonal antibody, or an antigen binding fragment thereof, that specifically interacts with at least one Nogo-66 receptor epitope, where the isolated neutralizing monoclonal antibody, or an antigen binding fragment thereof, comprises a sequence comprising a heavy chain variable region (VH region) comprising SEQ ID NO: 3 and a sequence comprising a light chain variable region (VL region) comprising SEQ ID NO: 4, or a sequence comprising a region heavy chain variable (VH region) comprising SEQ ID NO: 5 and a sequence comprising a light chain variable region (VL region) comprising SEQ ID NO: 6. |