http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2609912-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d03fb4fb7bfba6ac8c9ddad0475dfe5 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-04 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-10 |
| filingDate | 2008-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4559f90c71177336f5f56dfad0abfcce http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aaa2265c8621a960ca33e31f8ec156f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a0bd2e89a8c7f56dd10f3ed13b62cc9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbd6b0f081739018c0654edf995fe2d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f4b1822050d5f7c201cc722e4fca1bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d327f2f0c91acba2466f3503e352d0b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e1ed09611943edff78943aeed0d11a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7432935e09148fa231f22450c3c6049d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f440d50d96e3c21b9e56da336acc320 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29ef74132700bb1aa41a6b78d47711bb |
| publicationDate | 2017-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2609912-T3 |
| titleOfInvention | Compounds of 2,6-dioxo, -2,3-dihydro-1h-purine useful for the treatment of disorders related to the activity of the trpa1 channel |
| abstract | A compound of formula (VIII) or a pharmaceutically acceptable salt thereof, ** Formula ** where R1 and R2 are each independently C1-C6 alkyl, C2-C6 alkenyl or C2-C6 alkynyl, each being optionally substituted by 1 -4 R5; L is NR6C (O) or C (O) NR6, R3a is carbocycle, heterocyclyl, aryl, heteroaryl, and R3b is a 6-membered nitrogen-containing heteroaryl, each optionally substituted by 1-4 R7; each R5 is independently halo, hydroxy, alkoxy, amino, alkylamino, dialkylamino, cyano, nitro, amido, mido alkylation, dialkylamido, thioyl, sulfonyl, carbocycle, heterocyclyl, aryl, or heteroaryl; each R6 is independently H, C1-C6 alkyl, C1-C6 alkenyl, C1-C6 hydroxy alkyl, C1-C6 alkoxy alkyl, cyanoalkyl, haloalkyl, arylalkyl, S (O) alkyl, acyl, amino, amidyl, S (O) 2H, aryl, or alkoxyaryl; Each R7 is independently C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo, hydroxyl, alkoxy, oxo, aryl, heteroaryl, carbocycle, heterocyclyl, arylalkyl, heteroarylalkyl, cyclolalkyl, heterocyclylalkyl, aryloxy, arylamino alkoxy, , dialkylamino, thioyl, alkylthioyl, sulfonyl, sulfonamidyl, amido (for example, where the amide nitrogen is substituted by an alkyl group, or where the amide nitrogen together with two carbons to which it is attached, forms a ring ), hydroxyl alkoxy, alkoxy-C (O) OH, -C (O) Oalkyl, urea, sulfonylurea, acyl, nitro, or cyano, each optionally substituted with 1-3 R8; each R8 is independently C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo, hydroxy, alkoxy, oxo, aryloxy, amino, alkylamino, dialkylamino, C (O) OH, -C (O) O alkyl, thioyl , sulfonyl, sulfonamidyl, amido (for example, where the amide nitrogen is substituted by an alkyl group, or where the amide nitrogen together with two carbons to which it is attached, forms a ring), urea, sulfonylurea, acyl, nitro, cyano, carbocycle, heterocyclyl, aryl, or heteroaryl; R9 is H, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, halo, C1-C6 haloalkyl, hydroxyl, alkoxy, aryloxy, arylalkoxy, amino, alkylamino, dialkylamino, thioyl, alkylthioyl, sulfonyl, sulfonamidyl, amido, urea, sulfonylurea, acyl, nitro, or cyano, each optionally substituted by 1-3 R8; and m is 1, 2, 3, 4, 5, or 6. |
| priorityDate | 2007-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 887.