abstract |
A pharmaceutical composition for inhalation administered separately, sequentially or jointly, comprising drugs containing an amine in the form of a dry powder selected from the group consisting of aclidinium, glycopyrronium, darotropium, indacaterol, vilanterol, carmoterol or olodaterol or its salt or pharmaceutically acceptable ester, either in enantiomerically pure form or as a racemic mixture in admixture with a pharmaceutically acceptable carrier, other than lactose, said pharmaceutically acceptable carrier comprising fine and coarse particles wherein the pharmaceutically acceptable carrier is selected from the group consisting of mannitol, glucose, trehalose, cellobiose, sorbitol and maltitol or a combination of two or more of them and the fine to coarse particle ratio is between 0.01 - 0.25 by weight |