http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2609596-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
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| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-28 |
| filingDate | 2013-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c266f16ce7493f36ad4c15d457dd0ff7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bccea4c89ee26955d875603594b822a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc4f3668a1fbd4c7a790a12c9122d602 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50700bfd3947ca7bbbc708ca86e56bba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3e535c49be98b66a0ead5f181ead7b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82970fae11b554cde2ec5ef76725707f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_897b45846e78f4a3f45d812330adb47d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e3ab41a8d43ccd47efa4a097b7823c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_745e0f6f8a4539bb008e833da00ebc3b |
| publicationDate | 2017-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2609596-T3 |
| titleOfInvention | Novel androgen receptor selective modulators |
| abstract | A compound of Formula 1, 2 or 3: ** Formula ** in which A is N or -CR0--, in which R0 is hydrogen, straight or branched chain C1-C6 alkyl, C1-C6 chain perfluoroalkyl linear or branched, aryl, perfluoroaryl, alkylaryl, heteroaryl; or alkylheteroaryl X and Y are independently -CH2--, -CHRa--, or -CRaRb--, in which Ra and Rb are independently C1-C6 straight or branched chain alkyl, aryl, alkylaryl, heteroaryl or alkylheteroaryl; or, Ra and Rb together form a chain comprising - (CH2) j--, - (CHRc) j-- or - (CRcRd) j--, in which Rc and Rd are independently C1-C6 alkyl of linear or branched chain, C1-C6 straight or branched chain perfluoroalkyl, aryl, alkylaryl, heteroaryl or alkylheteroaryl; in which j is 2; 3, 4 or 5 Z is -CRe - or -N--, where Re is hydrogen, straight or branched chain C1-C6 alkyl, straight or branched chain C1-C6 perfluoroalkyl, aryl, alkylaryl, heteroaryl , alkylheteroaryl; R1 is hydrogen, straight or branched chain C1-C6 alkyl, aryl, straight or branched chain C1-C6 perfluoroalkyl, alkylaryl, heteroaryl, alkylheteroaryl, straight or branched chain C1-C6 alkoxycarbonyl, C1-C6 alkylaminocarbonylamino linear or branched, straight or branched chain C1-C6 alkyloxycarbonylamino, straight or branched chain C1-C6 alkylcarbonylamino, or straight or straight chain C1-C6 alkylaminocarbonyl; R2 is independently hydrogen or C1-C6 straight or branched chain alkyl; or, R1 and R8 together form a chain comprising - (CH2) m-, - (CHRf) m- or - (CRfRg) m-, in which Fr and Rg are independently C1-C6 straight or branched chain alkyl , aryl, alkylaryl, heteroaryl or alkylheteroaryl; in which m is 2; 3, 4 or 5; R9 and R10 are independently hydrogen or C1-C6 straight or branched chain alkyl, C1-C6 straight or branched chain perfluoroalkyl, cyano, hydroxyl, amino, carboxy, aryl, heteroaryl, or, R9 and R10 together form a chain comprising - (CH2) p-, - (CHRh) p- or - (CRhRi) p-, wherein Rh and Ri are independently straight or branched chain C1-C6 alkyl, aryl, alkylaryl, heteroaryl or alkylheteroaryl; in which p is 2; 3, 4 or 5; Q is --CO--, - (CH2) q-, - (CHRs) q- or - (CRsRt) q-, in which Rs and Rt are independently straight or straight chain C1-C6 alkyl, aryl , alkylaryl, heteroaryl or alkylheteroaryl; in which q is 0, 1, 2 or 3; and, where n is 0, 1, 2, 3, 4 or 5; or, a pharmaceutically acceptable salt thereof. R3 and R4 are independently hydrogen, straight or branched chain C1-C6 alkyl, straight or branched chain C1-C6 perfluoroalkyl, straight or straight chain C1-C6 perfluoroalkoxy, halogen, cyano, hydroxyl, amino, carboxy, aryl, heteroaryl , C1-C6 straight or branched chain alkoxycarbonyl, straight or branched chain C1-C6 alkylaminocarbonylamino, or straight or branched chain C1-C6 alkylaminocarbonyl or; R5 and R6 are independently hydrogen or C1-C6 straight or branched chain alkyl, C1-C6 straight or branched chain perfluoroalkyl, cyano, hydroxyl, amino, carboxy, aryl, heteroaryl, or, R5 and R6 together form a chain comprising - (CH2) k-, - (CHR7) k- or - (CR7aR7b) k-, in which R7, R7a, and R7b are independently straight or branched chain C1-C6 alkyl, C1-C6 chain perfluoroalkyl linear or branched, aryl, alkylaryl, heteroaryl or alkylheteroaryl; in which k is 2; 3, 4 or 5; R8 is hydrogen, C1-C6 straight or branched chain alkyl, C1-C6 straight or branched chain perfluoroalkyl, aryl, aryl substituted with one, two or three fluorine atoms, perfluoroaryl, alkylaryl, heteroaryl; or, alkylheteroaryl; |
| priorityDate | 2012-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 327.