http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2609299-T3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7d999bb6ab478a7ed29b45a75d9190d |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 |
filingDate | 2009-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c6c2af24ad6c05bc5768d6675152f1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6be80f21bfd4ba0ecd727fcc4f484d8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_654a57f5f1632e6ea932dbc4bd00ce9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65185956ff8615abf337f5bf88bfca42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cf69e72ac9525a1a8cec8087472fd71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1473fb9e2ddb6c4cd5d4f0e0cfef4cf0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4b6db8e5511e80e20c337ff19d1e621 |
publicationDate | 2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2609299-T3 |
titleOfInvention | Solvent resistant diafiltration of peptides, PNA or oligonucleotides |
abstract | A process for the preparation of a first compound selected from oligonucleotides and peptide nucleic acids; the process comprising: (i) synthesizing the first compound by liquid phase synthesis in an organic solvent; and (ii) separating the first compound formed in step (i) from a second compound, which is a reaction byproduct of the synthesis of the first compound and / or an excess of a reagent used for the synthesis of a first compound, in where: the synthesis of the first compound in step (i) implies one or more coupling or deprotection reactions; the first and second compounds are dissolved in an organic solvent and separated by a diafiltration process using a membrane that is stable in the organic solvent and that provides a rejection for the first compound that is greater than the rejection for the second compound; The first compound is modified by subjecting it to one or more coupling and / or deprotection reactions after separation. |
priorityDate | 2008-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.