| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90d41c5c08b4cc27008c8d448154a71f |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate |
2006-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f8c2549fb079757fc7386c3bae13b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56bf6f42340c26053297f2f4de157b4f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1300a4054b01893287211467a418cadf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_649fd920974ea53ad2a96d9682c3593e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_969be4285157489cd311860285f9d718
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e9967c595954522e3c648aeb4c65d63 |
| publicationDate |
2017-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2606762-T3 |
| titleOfInvention |
Antibodies against CD38 for the treatment of multiple myeloma |
| abstract |
An antibody that binds to human CD38 (SEQ ID NO: 31), and that does not bind to a mutant CD38 where the serine moiety at position 274 has been replaced with a phenylalanine moiety (SEQ ID NO: 34) to the same degree that it binds to human CD38 (SEQ ID NO: 31), and that it does not bind to a mutant CD38 where the remaining glutamine at position 272 has been replaced with an arginine residue (SEQ ID NO: 33) to the same degree that binds to human CD38 (SEQ ID NO: 31); and wherein the antibody recognizes the KRN and VQTL motifs of human CD38 (SEQ ID NO: 31). |
| priorityDate |
2005-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |