Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_444a4400392d34e80d06c30c09a7e0fb |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-7158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-521 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1793 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
2011-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2017-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98b277922a7e6d0f1e0b738c446c3189 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79d6f3ab4e804af26c3d2a2a8084c818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf388708cbf01bf580b2096cb35c262f |
publicationDate |
2017-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2604108-T3 |
titleOfInvention |
Blockade of CCL18 signaling through CCR6 as a therapeutic option in fibrotic diseases and cancer |
abstract |
A pharmaceutical composition comprising a compound capable of inhibiting the activity and / or expression of CCL18 or CCL20 for use in treatment, wherein the compound capable of inhibiting the activity and / or expression of CCL18 or CCL20 is selects from the group consisting of (1) an isolated soluble CCR6 receptor polypeptide comprising or consisting of an amino acid sequence that is selected from the group consisting of: (a) an amino acid sequence presenting an identity of at least 80% with the sequence according to SEQ ID NO .: 1; and (b) a fragment of the amino acid sequence according to (a); wherein said isolated soluble CCR6 receptor polypeptide is capable of binding to CCL18 and / or CCL20 and wherein said isolated soluble CCR6 receptor polypeptide does not comprise a transmembrane domain; (2) the isolated soluble CCR6 receptor polypeptide according to (1), wherein the amino acid sequence according to (a) comprises at least 8 consecutive amino acids from the sequence according to SEQ ID NO .: 1. |
priorityDate |
2010-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |