http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2601849-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37f4922dfb7777b019e504b885211b8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8381e33e1ea40966833271a143071d90 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-4015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-4075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-4006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6512 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6512 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-40 |
| filingDate | 2010-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_682f62d62157042df952c06b3a9f7764 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_322f9816fa8f5e96ca36eea915c08043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29fc5fb9d0ab99e2bf9d98704624376c |
| publicationDate | 2017-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2601849-T3 |
| titleOfInvention | Phosphonate syntheses for the synthesis of phosphonate derivatives that show better bioavailability |
| abstract | Compounds of formula (I-1): ** Formula ** in which R1 represents H, a linear or branched C1-C6 alkyl group or a group ((CH2) m-R2 with R2 being selected from the group comprising hydrogen, halogen , OH, N3, NH2, epoxy groups, leaving groups selected from halogen and sulfonyl group and carbonyl groups and m is an integer from 0 to 5, n is an integer from 0 to 5, X and Y independently represent hydrogen, halogen or a linear or branched C1-C6 alkyl group or a hydroxyethyl group, and R 'and R "independently from each other: (a) represent a group selected from the group comprising (i) an oxymethylcarbonyl group of formula (2) * * Formula ** in which R1 and R'1 are independently from each other hydrogen or a C1-C4 alkyl group and R'2 is a linear or branched C1-C6 alkyl group or a linear or branched C1-C6 alkoxy group (ii ) a thioethylcarbonyl group of formula (3) ** Formula ** in which R3 is a linear or branched C1-C6 alkyl group (iii) a a lipophilic chain selected in the group comprising, but not limited to, hexadecyloxypropyl (HDP), octadecyloxyethyl, oxyloxypropyl, and oleyloxyethyl esters, or (b) R 'and R "form with the phosphate atom to which they are attached cycloalkyl group of formula (4) ** Formula ** in which R4, R5, R6, and R7 each independently represent a linear or branched C1-C6 alkyl or aryl group or R4, and R7 independently represent a C1- alkyl group Linear or branched C6 or aryl or R5 and R6 together form an aromatic ring, said aromatic ring being optionally substituted, for example, with a chloride atom. |
| priorityDate | 2009-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.