http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2598830-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a98cb1b197f761c87cd3caf32bc247e2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-501 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4725 |
| filingDate | 2012-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0733009f8f9a5ca1a98ec67cc0a81a8d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0de59d9e092d48dbac7dd7bbc7f0457 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9e18eb26ef1f7bf9fb80e51b3af2e5c |
| publicationDate | 2017-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2598830-T3 |
| titleOfInvention | Bicyclic compounds or salts thereof for use in the treatment of cancer |
| abstract | A compound represented by the following general formula (I) or a salt thereof: ** Formula ** wherein at least one of X1, X2, X3 and X4 represents N or N-oxide and the rest of them are the same or different and each represents C-R2; any one or two of Y1, Y2, Y3 and Y4 represent C-R4 and the rest of them are the same or different and each represents CH or N; R1 represents an optionally substituted monocyclic or bicyclic unsaturated heterocyclic group having 1 to 4 heteroatoms selected from N, S, and O; wherein, when the substituent is an alkyl group, an alkoxy group, an alkylamino group, an acyl group, a carbamoyl group, an acylamino group, an aromatic hydrocarbon group, an unsaturated heterocyclic group, or a saturated heterocyclic group, the substituent is optionally substituted; R2 represents a hydrogen atom, an optionally substituted alkyl group having 1 to 6 carbon atoms, an optionally substituted cycloalkyl group having 3 to 7 carbon atoms, or an optionally substituted alkenyl group having 2 to 6 carbon atoms carbon; R3 represents a cyano group or -CO-R5; R4 represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, -CO-R6, -N (R7) (R8 ) or -S-R9; R5 represents a hydroxyl group, an amino group, or an optionally substituted alkylamino group having 1 to 6 carbon atoms; wherein, when the substituent is an alkylamino group, the alkyl moiety of the substituent is optionally substituted with a hydroxyl group; R6 represents a hydroxyl group, an amino group optionally having a hydroxyl group, or an optionally substituted alkylamino group having 1 to 6 carbon atoms; R7 and R8 are the same or different and each represents a hydrogen atom, an optionally substituted alkyl group having 1 to 6 carbon atoms, an optionally substituted cycloalkyl group having 3 to 7 carbon atoms, an aromatic hydrocarbon group optionally substituted, an optionally substituted saturated heterocyclic group or an optionally substituted unsaturated heterocyclic group, or R7 and R8 together form a saturated heterocyclic group together with the nitrogen atom attached thereto; and R9 represents an optionally substituted cycloalkyl group having 3 to 7 carbon atoms, or an optionally substituted aromatic hydrocarbon group; wherein the optional substituent is a halogen atom, a hydroxyl group, a cyano group, an amino group, a nitro group, an oxo group, a carboxyl group, a carbamoyl group, a linear or branched alkyl group having 1 to 6 carbon atoms, a cycloalkyl group having 3 to 7 carbon atoms, an alkenyl group having 2 to 6 carbon atoms, an alkynyl group having 2 to 6 carbon atoms, a linear or branched alkoxy group having 1 to 6 carbon atoms, an acyl group that is an alkanoyl group having 1 to 6 carbon atoms, or an aroyl group having 7 to 12 carbon atoms, an acyloxy group that is a substituted oxy group with the acyl group defined above, an alkoxycarbonyl group that is a carbonyl group substituted with the alkoxy group defined above, a saturated heterocyclic group that is a 5 to 10 membered monocyclic or bicyclic saturated heterocyclic group having 1 to 4 hete roatoms selected from N, S, and O, an unsaturated heterocyclic group that is a 5 to 10 membered monocyclic or bicyclic unsaturated heterocyclic group having 1 to 4 heteroatoms selected from N, S, and O, an aromatic hydrocarbon group having 6 to 14 carbon atoms, a haloalkyl group which is a group in which from one to all the hydrogen atoms of the alkyl group as defined above are replaced by the halogen atom or atoms, an aralkyl group which is an alkyl group linear or branched having 1 to 6 carbon atoms substituted with an aromatic hydrocarbon group having 6 to 14 carbon atoms, an unsaturated heterocyclic alkyl group which is the above defined alkyl group substituted with the unsaturated heterocyclic group which is defined above, an alkylamino group that is an amino group monosubstituted or disubstituted with the alkyl group as defined above, an acylamino group that is an amino group substituted with the acyl group defined above, an alkoxycarbonylamino group that is an amino group substituted with the alkoxycarbonyl group defined above, an aralkyloxy group that is an oxy group having the aralkyl group defined above, an aminoacyloxy group which is an oxy group substituted with the above defined acyl group attached to an amino group, an unsaturated heterocyclic acyloxy group which is an oxy group substituted with the above defined acyl group attached to the defined unsaturated heterocyclic group above and an alkyl unsaturated heterocyclic group. |
| priorityDate | 2011-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 611.