http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2598279-T3

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filingDate 2011-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dc3aaaaa808f66d47e8f0d94853e8ed
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publicationDate 2017-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2598279-T3
titleOfInvention Phenylacetamides and substituted phenylpropanamides and their use
abstract Compound of formula (I) ** Formula ** in which A represents a bond or -C (R6AR6B) -, in which R6A represents hydrogen, (C1-C4) alkyl or trifluoromethyl, R6B represents hydrogen or (C1- alkyl) C4), R1 represents (C1-C6) alkyl, (C2-C6) alkenyl, (C2-C6) alkynyl or (C3-C7) cycloalkyl, in which (C1-C6) alkyl, (C2-C6) alkenyl, and (C2-C6) alkynyl may be substituted with 1 to 3 substituents selected independently from one another from the group consisting of deuterium, halogen, cyano, oxo, hydroxy, trifluoromethyl, (C3-C7) cycloalkyl, (C1-C6) alkoxy, trifluoromethoxy and phenyl, in which (C3-C7) cycloalkyl can be substituted with 1 or 2 substituents selected independently of one another from the group consisting of (C1-C4) alkyl, oxo, hydroxy, (C1-C4) alkoxy and amino , and in which (C1-C6) alkoxy can be substituted with 1 or 2 substituents selected independently from one another from the group consisting of amino, hydroxy, (C1-C4) alkoxy, hydroxycar bonyl and (C1-C4) alkoxycarbonyl and in which phenyl may be substituted with from 1 to 3 substituents selected independently of one another from the group consisting of halogen, cyano, nitro, (C1-C4) alkyl, trifluoromethyl, hydroxy, hydroxymethyl , (C1-C4) alkoxy, trifluoromethoxy, (C1-C4) alkoxymethyl, hydroxycarbonyl, (C1-C4) alkoxycarbonyl, (C1-C4) monoalkylaminocarbonyl and (C1-C4) dialkylaminocarbonyl, and where (C3-) cycloalkyl C7) may be substituted with 1 or 2 substituents selected independently from each other from the group consisting of fluoro, (C1-C4) alkyl, (C1-C4) alkoxy, hydroxy, amino and oxo, R2 represents benzothienyl, phenyl, thienyl or furyl, in which benzothienyl, phenyl, thienyl and furyl can be substituted with 1 to 3 substituents selected independently of one another from the group consisting of halogen, cyano, nitro, (C1-C4) alkyl, trifluoromethyl, hydroxy, (C1-alkoxy) -C4) and trifluoromethoxy, R3 represents a g group of formula ** Formula ** in which represents the point of attachment to the nitrogen atom, L represents (C1-C4) alkanediyl, in which (C1-C4) alkanediyl can be substituted with from 1 to 3 independently selected substituents from each other from the group consisting of fluorine and (C1-C4) alkyl, R7A represents hydrogen or (C1-C4) alkyl, R7B represents hydrogen or (C1-C4) alkyl, or R7A and R7B together with the carbon atom at which are attached form a 3- to 6-membered carbocycle, R8 represents hydroxycarbonyl, (C1-C4) alkoxycarbonyl, aminocarbonyl, (C1-C4) monoalkylaminocarbonyl, or (C1-C4) dialkylaminocarbonyl, R9 represents hydroxy, trifluoromethoxy, (C1-C4 alkoxy ), hydroxycarbonyl, (C1-C4) alkoxycarbonyl, aminocarbonyl, (C1-C4) monoalkylaminocarbonyl, or (C1-C4) dialkylaminocarbonyl, R4 represents 5- to 10-membered phenyl, naphthyl, or heteroaryl, wherein 5-phenyl, naphthyl, and heteroaryl a 10 can be substituted with from 1 to 3 selected substituents s independently of one another from the group consisting of halogen, cyano, nitro, (C1-C4) alkyl, difluoromethyl, trifluoromethyl, hydroxy, (C1-C4) alkoxy, difluoromethoxy and trifluoromethoxy, R5 represents hydrogen, deuterium, trifluoromethyl or alkyl ( C1-C4), and its salts, solvates and solvates of the salts.
priorityDate 2010-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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