http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2598105-T3

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b09f893b262cefd50c5e76c4b85d1c0a
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-803
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-803
filingDate 2014-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95d34b75a0fb3a0bd83a28d1350937fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b1e466b610ca0f9be074aaaf00ce617
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed69bf73bf8cc1207b09d99a0ec0ef16
publicationDate 2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2598105-T3
titleOfInvention Method for the preparation of 6-trifluoromethylpyridine-3-carboxylic acid derivatives from trifluoroacetylacetic acid
abstract Method for the preparation of the compound of formula (I) ** Formula ** the method comprises a step (Step S1); the step (Step S1) comprises a reaction (ReacS1); The reaction (ReacS1) is a reaction of a compound of formula (II) with a compound of formula (III) and a compound of formula (IV); the compound of the formula (II) is chosen from the group consisting of a compound of formula (II-1), a compound of formula (II-2), a compound of formula (IIa), and mixtures thereof; ** Formula ** R1 is selected from the group consisting of C1-10 alkyl, C3-8 cycloalkyl, C (O) -O-C1-4 alkyl, CH> = CH2, benzyl, phenyl and naphthyl; C1-10 alkyl of R1 is unsubstituted or substituted with 1, 2, 3, 4 or 5 substituents, identical or different, chosen from the group consisting of halogen, OH, OC (O) C1-5 alkyl, O- C1-10 alkyl, S-C1-10 alkyl, S (O) -C1-10 alkyl, S (O2) -C1-10 alkyl, O- C1-6 alkylene-O-C1-6 alkyl, C3-8 cycloalkyl and 1,2,4-triazolyl; the benzyl, phenyl and naphthyl groups of R1 are independently from each other unsubstituted or substituted with 1, 2, 3, 4 or 5 identical or different substituents chosen from the group consisting of halogen, C1-4 alkoxy, NO2 and CN; Y is selected from the group consisting of C1-6 alkoxy, O- C1-6 alkylene-O-C1-6 alkyl, NH2, NHR4 and N (R4) R5; R4 and R5 are identical or different and independently from each other C1-6 alkyl, or together represent a tetramethylene or pentamethylene chain; R10 is chosen from the group consisting of C1-8 alkyl, C3-10 cycloalkyl and phenyl, said phenyl is unsubstituted or substituted with 1 or 2 identical or different substituents independently selected from among the group consisting of halogen, cyano , nitro, C1-6 alkyl and phenyl; R20 is selected from the group consisting of C1-6 alkyl, O (CO) CH3, O (CO) CF3, and OSO3H.
priorityDate 2013-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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