http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2596369-T3

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filingDate 2012-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50a5b8951943271dd1b4ab2978bee635
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb42fdc42c0af82c957a2ee45b64fae0
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publicationDate 2017-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2596369-T3
titleOfInvention N-heterotricyclic antibiotics
abstract A compound of formula I: ** Formula ** where A1 represents -O-, -S- or -CH2-; A2 represents -CH2- or -O-; A3 represents C3-C8 cycloalkylene; saturated or unsaturated 4- to 8-membered heterocyclodiyl with 1, 2 or 3 heteroatoms selected from nitrogen or oxygen, said group A3 being unsubstituted or substituted by one or more substituents each being independently selected from the others for fluorine, chlorine, or bromine atoms or iodine, carboxy, alkyl, alkoxy or mono- or di (C1-C4 alkyl) amino groups, OH,> = O, SH,> = S, NH2,> = NH, cyano, NO2, C1-C4 alkoxycarbonyl, morpholinocarbonyl and C1-C4 hydroxyalkyl; A4 represents -C (> = O) -; G represents an aryl or heteroaryl group to which cycloalkane and / or heterocycloalkane rings can be further condensed, in which aryl groups contain one or more rings and 6 to 14 carbon atoms, heteroaryl groups contain one or more rings and 5 to 14 ring atoms containing one or more oxygen, nitrogen or sulfur atoms in the ring, cycloalkane groups are saturated or partially unsaturated cyclic groups containing one or more rings and from 3 to 14 carbon atoms and heterocycloalkane groups are saturated or partially unsaturated cyclic groups containing one or more rings and from 3 to 14 carbon atoms, in which one or more carbon atoms in the ring are each independently replaced by the other with an oxygen, nitrogen or sulfur and said aryl and heteroaryl groups are unsubstituted or substituted by one or more substituents each independently selected from the others from fluorine, chlorine, bromine or iodine atoms, carboxy, alkyl, alkoxy or mono- or di (C1-C4-alkyl) amino, OH, SH, NH2, cyano and NO2 groups and in the case of heteroaryl groups also unsubstituted heteroaryl groups and said cycloalkane or heterocycloalkane groups are substituted by one or more substituents each being independently selected from the others from fluorine, chlorine, bromine or iodine atoms, carboxy, alkyl, alkoxy or mono- or di (C1-C4-alkyl) amino groups, OH,> = O, SH,> = S, NH2,> = NH cyano and NO2; X1 represents a nitrogen atom or CR1; R1 represents a hydrogen atom or a halogen atom; m is 0 or 1; n is 1; the group - (CH2) n- is unsubstituted; and p is 0 or 1; or a pharmaceutically acceptable salt thereof.
priorityDate 2011-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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