http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2593608-T3

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_981a37900e6991fb373304ed2ba5a703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3bca1d4871a7a6bebce3049b6960c25
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D251-20
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D251-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-58
filingDate 2013-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_446614ee423b1457d45e4de69f184a53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5720ffce23b99200770f034215e97df7
publicationDate 2016-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2593608-T3
titleOfInvention Continuous procedure for the production of ortho substituted anilines in a flow reactor
abstract Process for continuously preparing compounds of the formula (4) ** Formula ** in which R1 represents (C1-C6) alkyl, substituted alkyl, aryl or substituted aryl, R2 represents an electron acceptor substituent or activator selected from the group consisting of - CN, - NO2, - CO-R1 ', where R1' is as defined for R1 and R1 'is equal to or different from R1, - CO-X, where X represents OR1' ', SR1' 'or NR2'R2 '', where R1 '' is as defined for R1 and R1 '' is the same or different from R1 and where R2 'and R2' each independently represent H, (C1-C6) alkyl, alkyl (C1-C6) substituted, aryl or substituted aryl or R2 'and R2' 'form a ring, - SO (n) -R1' '', where R1 '' 'is as defined for R1, where R1' '' in each case the same or different from R1 and n being 0, 1 or 2, - aryl and - heteroaryl, R3 represents H, (C1-C6) alkyl, substituted alkyl, aryl or substituted aryl, R4a to R4d each is selected regardless of the group consisting of hydrogen, fluorine, clo ro, bromine, iodine, CN, NO2 and (C1-C6) alkyl, where the alkyl moiety is unsubstituted or substituted with one or more substituents selected from the group consisting of fluorine, chlorine, (C1-C4) alkoxy or cycloalkyl (C3-C7), cycloalkyl (C3-C7), where the cycloalkyl moiety is unsubstituted or substituted with one or more substituents selected from the group consisting of fluorine, chlorine, (C1-C4) alkyl or cycloalkyl (C3-C7) or (C1-C4) alkoxy, (C1-C6) alkoxy, wherein the alkoxy moiety is unsubstituted or substituted with one or more substituents selected from the group consisting of fluorine, chlorine, (C1-C4) alkoxy or (C3-) cycloalkyl C7), cycloalkoxy (C3-C7), where the cycloalkoxy moiety is unsubstituted or substituted with one or more substituents selected from the group consisting of fluorine, chlorine, (C1-C4) alkyl or (C1-C4) alkoxy, CO- X, where X represents OR1 '', SR1 '' or NR2'R2 '', where R1 '' is as defined for R1 and R1 '' is equal to or different from R1 and where R2 'and R2' 'representin each case independently of each other H, (C1-C6) alkyl, substituted (C1-C6) alkyl, substituted aryl or aryl or R2 'and R2' 'alternatively form a ring, phenyl or 1-naphthyl or 2-naphthyl or a heteroaromatic ring of five or six elements with 1 to 2 heteroatoms, the heteroatoms being selected independently from each other from the group consisting of O or N and the aryl or heteroaryl moieties being unsubstituted or substituted with one or more substituents selected from the group consisting of fluorine , chlorine, bromine, iodine, (C1-C4) alkyl, (C1-C4) alkoxy or (C3-C7) cycloalkyl or (C1-C4) alkylthio, and R5 represents H, (C1-C6) alkyl, (C1-alkyl) -C6) substituted, aryl or substituted aryl, in which the reactants used in a flow reactor in the presence of an organic solvent are - an aniline (Q)
priorityDate 2012-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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