| abstract |
Composition for inactivating a enveloped virus comprising at least one phospholipid-free lipid vesicle (nPLV) that can interact with said enveloped virus and a cyclodextrin that enhances the lipid exchange between said nPLV and the membrane of said enveloped virus, in which nPLV has no cholesterol, the concentration of cyclodextrin in the composition is between 0.01 mM and 10 mM and cyclodextrin is selected from the group comprising dimethyl-β-cyclodextrin, trimethyl-β-cyclodextrin, randomly methylated β-cyclodextrin, hydroxyethyl-β-cyclodextrin, 2-hydroxypropyl-β-cyclodextrin, 3- hydroxypropyl-β-cyclodextrin, 2,3-dihydroxypropyl-β-cyclodextrin, 2-hydroxyisobutyl-β-cyclodextrin, sulfobutyl ether of β-cyclodextrin, glucosyl-β -cyclodextrin and maltosyl-β-cyclodextrin or a combination thereof. |