| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2cb03ff309c31e766cf428b88c1dd9a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-723
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2011-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8be39807499ca2da367f3259916f3f0e |
| publicationDate |
2016-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2588981-T3 |
| titleOfInvention |
Smoothened mutant and methods of using it |
| abstract |
An isolated mutant SMO protein, comprising an amino acid sequence that is at least 95% identical to SEQ ID NO: 2, wherein said amino acid sequence consists of alanine (A) or lysine (K) at the position of Amino acid 518 of SEQ ID NO: 2, wherein said mutation confers at least a partial resistance of the mutated SMO protein to GDC-0449. |
| priorityDate |
2010-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |