| abstract |
Granule of the nucleus-cortex type that has a maximum size of 3 mm and adapted to float on the surface of the stomach liquid that includes: a) a solid neutral core b) an inner layer applied on said neutral core and containing an active principle whose The absorption site is located very high in the digestive tract, chosen from the group consisting of furosemide, tiapride, fuzosin, captopril, GHB, metformin, nifedipine, buprenorphine, modafinil, methadone, nalbuphine, tetrahydrocannabinol and an alkaline agent capable of generating a gaseous release in the presence of said stomach liquid, c) an outer coating layer. |