abstract |
A composition comprising: a segment of polypeptide that binds to collagen bound to a modulator of the PTH / PTHrP receptor; wherein the PTH / PTHrP receptor modulator is a PTH / PTHrP receptor agonist and comprises residues 1-33 of SEQ ID NO: 1, or PTH (SEQ ID NO: 7), or residues 1-14 of SEQ ID NO: 1, or residues 1-34 of SEQ ID NO: 7; or wherein the PTH / PTHrP receptor modulator is a PTH / PTHrP receptor antagonist and comprises residues 7-34 of SEQ ID NO: 7, or comprises residues 7-14 of SEQ ID NO: 7; and wherein the collagen-binding polypeptide segment comprises residues 38-158 of SEQ ID NO: 1, or is at least 90% identical to residues 38-158 of SEQ ID NO: 1. |