http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2580331-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f9462a534decd5a7db000321f2b14050 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-005 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J75-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575 |
filingDate | 2012-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc59f966eb7efb1a1cdbfaff606b67ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0795b9f90aeb527dd244a39a0fcb8072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_796a6046fbb3f214d55add1ec5a472a0 |
publicationDate | 2016-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2580331-T3 |
titleOfInvention | Sterol derivatives, method for preparing them, pharmaceutical compositions containing them and use thereof for the treatment of multiple glioblastomas |
abstract | The compound of formula (I) ** Formula ** where - A represents a group - (R1) n- in which R1 is an amino acid residue linked at its C-terminus and n> = 1 to 3, each R1 being identical or different, wherein the N-terminus of said amino acid is unsubstituted or substituted with a -C- (O) -R2 group wherein R2 is a mono or polycyclic C6-C14 arylalkyl group; a mono or polycyclic C5-C14 group which may comprise one or more heteroatoms, which may be the same or different; a mono or polycyclic C6-C14 arylakyloxy group or a mono or polycyclic C5-C14 heteroarylakyloxy group which may comprise one or more heteroatoms, which may be the same or different, a -C (O) -NH-R3 or -C (S ) -NH-R3 where R3 is hydrogen; a linear or branched C1-C12 alkyl group, unsubstituted or substituted with a group selected from OR, NRR ', NHR and SR, where R and R' independently represent hydrogen, a linear C1-C12 alkyl or an unsubstituted aryl; an aryl group unsubstituted or substituted with a group selected from OR, NRR ', NHR and SR as defined above; an acyl group; a formyl group; a sulfonyl group; a sulfinyl group, a silyl group unsubstituted or substituted with a mono or polycyclic C6-C14 aryl group, unsubstituted or substituted with at least one linear or branched C1-C6 alkyl; an allyl group; a sugar residue; a -C (O) -OR4 group in which R4 is a linear or branched C1-C12 alkyl unsubstituted or substituted with a group selected from OR, NRR ', NHR and SR, as defined above; an amide group; a thioamide group; a sulfonamide group, a -C (O) -R5 group where R5 is a saturated C5-C14 heterocycle comprising 1 or 2 heteroatoms, unsubstituted or substituted with at least one linear or branched C1-C6 alkyl or a group selected from OR , NRR ', NHR and SR, where R and R' independently represent hydrogen, a C1-C12 alkyl or an unsubstituted aryl. - B represents a group -C (O) -R6 where R6 is hydrogen; a C1-C12 alkyl, preferably C1-C6, linear or branched, unsubstituted or substituted with a group selected from OR, NRR ', NHR and SR, as defined above; an aryl group, unsubstituted or substituted by a group selected from OR, NRR ', NHR and SR, as defined above; or R6 otherwise represents OR7, where R7 is a C1-C12, preferably C1-C6, linear or branched alkyl. |
priorityDate | 2012-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.