| abstract |
A composition for use in improving cognitive function in a subject with Down syndrome, which comprises a compound selected from pentylenetetrazole, picrotoxin, bilobalid and ginkgolide B, and a pharmaceutically acceptable carrier, said composition administered in doses of less than one dose. that experimentally sensitizes a crisis in the subject, and in which the doses are administered to the subject for an effective period of time to achieve an improvement in cognitive function, as measured using a protocol to assess cognitive function. |