| abstract |
Compounds of the formula (I): ** Formula ** characterized in that: R1 represents Het1 or Ar; R2, R3, independently of each other, represent Y or OY, or together also represent -O- (CH2) n-; R4 represents A or (CH2) nOA; L represents -CR2R3-, a single bond, - (CH2) n-, -CH (Hal) -, -C (Hal) 2-, - (CH2) nCH (OY) -, - (CH2) nCO-, - (CH2) nNH-, - (CH2) nCONY2-, -NYCO-, -NHCO-NH-, -NR4CO-, -NYSO2-, -C (> = NR4) -, -C (> = NCN) -, - CY (NY2) -, -CY (CN) -, -CY (O- (CH2) nCN) -, -CY (Het2) - or -CY (O- (CH2) nHet2) -; Y represents H or A; A represents unbranched or branched alkyl having 1-10 C atoms, in which, independently of each other, 1-7 H atoms can be replaced by Hal; Cyc represents cyclic alkyl having 3-7 C atoms, in which, independently of each other, 1-4 H atoms can be replaced by Hal; Ar represents phenyl that is unsubstituted or mono- or disubstituted by Hal, (CH2) pOY, R4, (CH2) pOR4, COOY, NY2, NYCOY and / or CN; Het1 represents mono- or bicyclic heteroaryl having 2-9 atoms of C and 1-4 atoms of N, O and / or S, which can be unsubstituted or mono- or disubstituted by Hal, (CH2) pOY, R4, (CH2 ) pOR4,> = O, COOY, NY2, NYCOY, CONY2, Cyc, Het2 and / or CN; Het2 represents a monocyclic saturated heterocycle having 2-7 atoms of C and 1-4 atoms of N, O and / or S, which can be unsubstituted or monosubstituted by A; Hal represents F, Cl, Br or I; m represents 0, 1 or 2; and n, p, independently of each other, represent 0, 1, 2, 3, 4 or 5, and / or the physiologically acceptable salts, tautomers and / or stereoisomers thereof, including mixtures thereof in all ratios. |