abstract |
A crystalline form I of (R) -7-chloro-N- (quinuclidin-3-yl) benzo [b] thiophene-2-carboxamide monohydrate hydrochloride, characterized by a powder X-ray diffractogram having peaks expressed as 2θ at one or both of 17.48 and 20.58 ± 0.20 degrees when measured against an internal silicon pattern, and characterized by an X-ray powder diffractogram that also has at least four peaks, six peaks, eight peaks or all peaks expressed as 2θ to 4.50, 9.04, 14.60, 15.14, 15.80, 16.60, 18.16, 18.44, 19.48, 21.74, and 25.46 ± 0.20 degrees when measured against an internal silicon pattern. |