abstract |
A double stranded RNA comprising hybridized complementary strands, in which at least one of said strands comprises a polyribonucleotide selected from the group consisting of: (i) complementary polyribonucleotides to at least 21 contiguous nucleotides of a target gene represented by any of the SEC ID No.: 23, 121 to 123, 157, 158, 230, 259, 503, 896, 1010, 1023 to 1025, 1040, 1061, 1113, 1437 and 1677, (ii) complementary polyiribonucleotides to at least 21 contiguous nucleotides of a target gene encoding the amino acid sequence represented by any of SEQ ID NO: 24, 260, 897 and 1114, and (iii) polyribonucleotides that have at least 85% sequence identity with the polyiribonucleotides of (i) or ( ii). |