http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2565243-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_681ff6871f0118f0ac26adb6337c6bec |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 2008-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a5f40bce7bc1ec879f21b4872450b30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2983a4214de8ec482696468651bf850 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbcdaf9faac00a15fcd69484364e0e83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1590095b742ec05a6d05f6c6a2521a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1fdfd1c76d2d02ad71ac5e15edd1180 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_173f307c6cc52c6f5330fd94b5e44488 |
| publicationDate | 2016-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2565243-T3 |
| titleOfInvention | Histone Deacetylase Inhibitors |
| abstract | A compound of the formula (1): ** Formula ** or an N-oxide, hydrate, solvate, pharmaceutically acceptable salt thereof, or a racemic or chimemic mixture, diastereomer, enantiomer or tautomer thereof, wherein T is NH2 or OH; A is arylene, which is optionally substituted; and X is where Y> = N, n1> = 1 and Z1 is selected from the group consisting of R12-OC (O) -N (R2), (C1-C6 hydrocarbyl) -O- (C1 hydrocarbyl -C6) -OC (O) -N (R2) -, (C1-C6 hydrocarbyl) -OC (O) NR2) - or R16-OC (O) -N (R2) -, in which R16 20 is selected from the group consisting of (hydrocarbyl C1-C6) -, Ar- (hydrocarbyl C1-C2) -, Het- (hydrocarbyl C1-C2) -, Hca- (hydrocarbyl C0-C2) - or Cak- (hydrocarbyl C0-C2) -; wherein each R2 is independently selected from the group consisting of hydrogen, (C1-C5 alkyl) -, Hca- (C0-C4 alkyl) -, Cak- (C0-C4 alkyl) -, R14-CO-, R14 -SO2-, R14-CO-NH- and R14-CO-O-, wherein each alkyl is optionally substituted; each R12 is independently selected from the group consisting of (C1-C6 hydrocarbyl) -, Ar- (C1-C6 hydrocarbyl) -, Het- (C1-C6 hydrocarbyl) -, Hca- (C0-C6 hydrocarbyl) -, Cak- (C0-C6 hydrocarbyl) - optionally substituted; and each R14 is independently selected from the group consisting of Ar- e (C1-C6 hydrocarbyl) - optionally substituted; wherein any moiety (C1-C6 hydrocarbyl) - is optionally substituted, and each Ar is independently an optionally substituted aryl, each Het is independently an optionally substituted heteroaryl, each Hca is independently an optionally substituted heterocycloalkyl, and each Cak is independently a cycloalkyl optionally substituted. |
| priorityDate | 2007-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.