Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d5de66fcc7c37934b48c684ca26e9cc0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ad46747489662de7b6bba94b18ef4156 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-321 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-315 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate |
2009-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fef9d4b6f3bd3e4fcc210918fe68fce4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d371dff0478602939373e08282489d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91bd3ae2db2e3906686dc8c6b7ba83ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a80d1350bbcb99f0672052de53ab9897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9211c67d8825e4b0802f24467888559f |
publicationDate |
2016-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2562658-T3 |
titleOfInvention |
Procedures and means for efficient skipping of exon 45 in the pre-mRNA of Duchenne muscular dystrophy |
abstract |
An antisense oligonucleotide, wherein said antisense oligonucleotide is capable of binding to a stretch of at least 21 nucleotides within the following nucleotide sequence within exon 45 of the dystrophin pre-mRNA: ** Formula ** and wherein said oligonucleotide has a length of at least 21 nucleotides and in which said antisense oligonucleotide does not consist of 5'-AACAGTTTGCCGCTGCCAATGCCA-3 ', 5'-CTGACAACAGTTTGCCGCTGCCCAA-3', 5'-GTTGCATTCAATGTTCTGACAAGAG-CTTCCTCCTCCTGT-3GCCAACAG-TTCTGACAACAGT-3GCCAACAGT-3 or 5'-ATTATTTCTTCCCCAGTTGCATTCA-3 '. |
priorityDate |
2008-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |