| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b433b63c2bf3e486e18496e27dbd96f3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6645ce16dbbcebca4cd8d594d264e9d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-0661 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-644
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate |
2011-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be0c35f49d29a0898be4f14afe81fabb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf0f7fbfe5b15cc688cb009bd37eb32c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c203732f10764f9031454e51760d3123
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c11165311a20e3b2a26a8d6ce7e966f |
| publicationDate |
2016-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2562421-T3 |
| titleOfInvention |
Methods and compositions to treat hemophilia B |
| abstract |
A protein comprising an engineered zinc finger protein DNA binding domain, wherein the DNA binding domain comprises four or five zinc finger recognition regions ordered F1 to F4 or F1 to F5 from the N-terminus to C-terminus, and where (i) when the DNA-binding domain comprises five zinc finger recognition regions, F1 to F5 comprise the following amino acid sequences: F1: QSGDLTR (SEQ ID NO: 4) F2: RSDVLSE (SEQ ID NO: 5) F3: DRSNRIK (SEQ ID NO: 6) F4: RSDNLSE (SEQ ID NO: 7) F5: QNATRIN (SEQ ID NO: 8); (ii) when the DNA binding domain comprises four zinc finger recognition regions, F1 to F4 comprise the following amino acid sequences: F1: RSDSLSV (SEQ ID NO: 10) F2: TSGHLSR (SEQ ID NO: 11) F3: RSDHLSQ (SEQ ID NO: 12) F4: HASTRHC (SEQ ID NO: 13). |
| priorityDate |
2010-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |