http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2560810-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_649f881bc11b1270366eb0b5ccab24fd |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
filingDate | 2011-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5461125d48f6ade69cee6ebafcc7c8d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e501e6f3b6c32254976418ea204598a3 |
publicationDate | 2016-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2560810-T3 |
titleOfInvention | Particulate medicinal composition |
abstract | Method for producing a particulate pharmaceutical composition, comprising: a) dissolving or dispersing a block copolymer unit having a hydrophobic polymer chain segment derived from a polyamino acid chain and a water soluble hydrophilic polymer chain segment composed of polyethylene glycol, and a lipid charged in a formation solution containing an organic solvent; b) remove the organic solvent by evaporation to form a solid or paste; c) combining the solid or paste with water or with an aqueous solution containing an additive with stirring to disperse the block copolymer unit and the charged lipid; d) further dispersing or spraying the resulting product by a method selected from ultrasound radiation, high pressure emulsification or extrusion to form a carrier composition; and e) carry out a freezing operation; wherein a drug is introduced that includes at least one biomachromolecule selected from the group consisting of a protein and a nucleic acid, adding the drug to the formation solution between steps a) and b) or adding the carrier composition to a solution of the drug between stages d) and e), in which the charged lipid carries a charge opposite to the drug load. |
priorityDate | 2010-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 151.