| abstract |
Aspartyl-tRNA synthetase (AspRS) polypeptide consisting of 50-200 amino acids in length, which has an anti-inflammatory activity and comprises amino acid residues 1-154, 1-171 or 1-174 of SEQ ID NO: 1, or an active fragment or variant of SEQ ID NO: 1, where the active fragment is at least 50 amino acids in length and the active fragment or variant has at least 80% sequence identity along its length with residues 1 -154, 1-171, or 1-174 of SEQ ID NO: 1, and where the AspRS polypeptide comprises an amphiphilic helix. |