http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2560236-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd8da0a02c7c4256f144f2c47dc0bab8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
| filingDate | 2009-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f40b5b6c3bd347a2d5f5d0c407bf6d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8349f04f310e11c6010d53b3be731861 |
| publicationDate | 2016-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2560236-T3 |
| titleOfInvention | Factor VII polypeptides that are modified and uses thereof |
| abstract | A method for producing a modified Factor VII (FVII) polypeptide, comprising: a) culturing a cell encoding the FVII modified polypeptide under conditions where the FVII modified polypeptide is expressed, where: the modifications are in positions corresponding to position 286 and position 298 in an FVII polypeptide having the amino acid sequence described in SEQ ID NO: 3 or in corresponding positions in loci aligned in an FVII polypeptide; the modification at position 286 is an amino acid replacement with an arginine (Arg, R); the modification at position 298 is an amino acid replacement with a glutamine (Gln, Q); and the modified FVII polypeptide shows increased coagulant activity compared to an unmodified FVII polypeptide that does not have the modifications at position 286; and b) recovering the expressed modified FVII polypeptide. |
| priorityDate | 2008-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 379.