abstract |
A cyclic amine compound of Formula (I): ** Formula ** or a pharmaceutically acceptable salt thereof, in which: A is selected from the group consisting of ** Formula ** in which: n> = 0 , 1 or 2 m> = 0 or 1 R1 and R2 are independently hydrogen, linear or branched C1-3alkyl or together joined together form a cyclopropyl ring; R3 is H or C1-3 linear or branched alkyl R4 and R5 are independently hydrogen, fluorine, C1-3 linear or branched alkyl or together bonded together form a cyclopropyl ring, Ar es-phenyl having: in position 4 a substituent selected from the group consisting of halogen, cyano, trifluoromethyl, or ii. in position 3 a substituent selected from the group consisting of halogen, cyano, trifluoromethyl, with the proviso that ii.a. when A is B, both R4 and R5 are fluorine, linear or branched C1-3alkyl or together bonded together form a cyclopropyl ring, ii.b. A is C and m is 0 ii.c. A is D and m is 1. - a 5-membered heteroaromatic ring containing 1 to 3 heteroatoms, in which said heteroatoms, independently of each other, are S, O or N; or - a 6-membered heteroaromatic ring containing 1 to 3 N. |