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filingDate 2011-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f20e10346718d3082675e366a465cf9
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publicationDate 2016-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2559226-T3
titleOfInvention Method to produce an aqueous dispersion of pseudopolyrotrotaxane
abstract A method for producing an aqueous dispersion of pseudopolyrrotaxane, the method comprising: a mixing step for dissolving a polyethylene glycol and a cyclodextrin in an aqueous medium to prepare a mixed solution; and a cooling step to continuously or intermittently cool the mixed solution in a flow state to precipitate particles of pseudopolyrotrotaxane, wherein the psedopolyrrotaxane particles contain the polyethylene glycol that is included in the cavities of the cyclodextrin molecules in a skewed manner. ; The mixed solution is heated to a temperature of 60 ° C to 90 ° C in the mixing stage; the titration temperature is from 5 ° C to 20 ° C in the cooling stage; the cooling stage is performed at a cooling rate of 0.01 at 30 ° C / min; and the particles in the aqueous dispersion of pseudopolyrrotaxane have an average particle size in volume analyzed using a particle size analyzer by laser diffraction of 1 to 200 μm.
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