abstract |
compound of formula 1.0: ** Formula ** or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2 and Q are independently selected and where: Q is: ** Formula ** R1 is selected from the group that it consists of: heteroaryl and substituted heteroaryl, wherein said substituted heteroaryl is substituted with 1 to 3 substituents independently selected from the group consisting of: -OH, alkoxy and -O-alkylene-O-alkyl; R2 is selected from the group consisting of: -O-alkyl and -S-alkyl; and R5 is selected from the group consisting of: (a) triazolyl-phenyl-, (b) triazolyl-phenyl-, wherein said phenyl is optionally substituted with 1 to 3 substituents independently selected from the group consisting of: halo and alkoxy, and (c) triazolyl-phenyl-substituted wherein said phenyl is optionally substituted with 1 to 3 substituents independently selected from the group consisting of: halo and alkoxy, and said triazolyl group is substituted with one or two substituents independently selected from the group consisting of: alkyl, hydroxy substituted alkyl, -alkylene-O-alkyl and amino, provided that, when said -alkylene-O-alkyl group is attached to the nitrogen of said triazolyl of (c), the alkylene moiety of said group -alkylene-O-alkyl is not -CH2-. |