http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2555454-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e1005fb53db203969fab84a916931d38 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65616 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 |
| filingDate | 2012-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b40fa06d7199aaaa0861aaf776494975 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_101b400bc31e353645d8e74f21dd7cbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01be33803be03e4fa56a8dc46c00998a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80cabca27eb1c63dd0da93e341489f21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67d33b3666158d24aa434e3198e9fb13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a257e566573db75101f84ba6faf11e54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed10e48c519077d2ce7bb5c5cd55785d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7708da5cce436795d6df550c8ace54f5 |
| publicationDate | 2016-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2555454-T3 |
| titleOfInvention | New family of analogues of NADP + or NADPH, its preparation and its application in therapeutic agents |
| abstract | Compounds of formula I: ** Formula ** in which: (i) X represents an electron acceptor group, chosen from the group comprising: - NO2, - CN, - CHO, - COOH, - CF3, - F, - CH> = C (CN) 2, - SO3H, - CONR9R10 or SO2NR9R10, in which R9 and R10 each independently represents hydrogen, a linear or branched (C1-C3) alkyl group, or an aryl group, - COR9, in which R9 represents a hydrogen, a linear or branched (C1-C3) alkyl group, or an aryl group, or - a tetrazolyl group, (ii) Y represents an electron donor group, chosen from the group that it comprises -NR9-, -OC (R19R14) - or -SC (R19R14) -, in which: - R19 is chosen from: - a hydrogen, - a linear (C1-C8) alkyl group, in particular an ethyl, being said alkyl group optionally substituted with one or more groups selected from: -OH group, -NH2 group, -COOH group, CONH-arylCOOH group or NHCO-aryl-COOH group or NHCOarylsulfate group, or NHCOarylsulfonate group, wherein the aryl group e is chosen ntre phenyl, naphthyl or biphenyl, or - a water-soluble organic group, in particular PEG, - R14 represents a hydrogen or a linear or branched (C1-C4) alkyl group, optionally substituted with -OH. (iii) A represents a bond chosen from the group comprising: (a) -C≡C-, or (b) ** Formula ** in which: - M1 and M2 independently represent each other H, F, Cl, Br or I, n is an integer chosen from 1, 2 or 3, (iv) each of R1, R2, R3, R4, R5, R6, R7 or R8 is independently selected from the group comprising: - H, - F, Cl, Br, I, - a linear or branched (C1-C4) alkyl, optionally substituted with one or more substituents chosen from: - OH, - NR11R12, in which R11 and R12 each independently represents the another a hydrogen or a linear or branched (C1-C3) alkyl group, or - COOR11, wherein R11 represents a hydrogen or a linear or branched (C1-C3) alkyl group, - CONHR13 or NHCOR13, in which R13 represents a linear or branched (C1-C4) alkyl group, (v) L represents a spacer group selected from the group comprising: ** Formula ** in which myq each independently represents the other an integer chosen from 0 to 5, said groups being optionally substituted with one or more OH, (vi) B represents the following formula II: ** Formula ** |
| priorityDate | 2011-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 274.